The consequence of a reversal sign

Following an uncomplicated post-dates pregnancy, delivery was accomplished by cesarean section for sustained fetal bradycardia.  Apgars scores were 1.5.5 and 1, 5 and 10 minutes. The initial blood gas was 6.42 and cord gas was 6.76.  Lactate was 17.2.  Head cooling was performed.  He experienced neonatal seizures.

Exponential apparent diffusion images at 4 days of age showing the disparity between the cerebellum and the supratentorial brain, a reversal sign.  See Kavanagh EC. The reversal sign. Radiology. 2007 Dec;245(3):914-5.

Apparent coefficient diffusion showing the disparity between the cerebellum and the supratentorial brain, a reversal sign.

Axial T2 propellar imaging at 15 months showing extensive diffuse damage to the supratentorial brain.

Axial T2 FLAIR imaging at 15 months.