Inspired by a patient
Sinha R, Singh S. Quivering Chin Syndrome. Neuropediatrics. 2023 Apr;54(2):159-160. doi: 10.1055/s-0042-1760103. Epub 2022 Dec 31. PMID: 36586402.
A 4-year-old neurotypical boy presented with unprovoked, involuntary intermittent tremulousness of the chin lasting for few minutes to hours, noted from 18 months of age with no family history. These movements were absent during sleep. The neurological examination, neuroimaging, and electroencephalography was otherwise normal. Surface electromyography of the mentalis muscle demonstrated a tremor frequency of 8 Hz. Quivering chin syndrome is a rare movement disorder. It may be sporadic or inherited in an autosomal dominant fashion with incomplete penetrance with locus on chromosome 9(9q13-q21). These involuntary, paroxysmal, rhythmic, movements of the chin and/or lower lip may last from seconds to hours. Episodes occur spontaneously or may be precipitated by stress and emotion. Usually no treatment is required. When indicated, injection of low-dose botulinum toxin into the mentalis muscle or low-dose clonazepam may be helpful. Recognition of this rare entity is important to avoid unnecessary investigations.
No comments:
Post a Comment