Jun Kubota, Norimichi Higurashib, Daishi Hiranob, Hirotaka
Isonoa, Haruka Numata, Takayuki Suzukia, Daisuke Kakegawaa, Akira Itoa, Manabu
Yoshihashic, Takeru Itoa, Shin-ichiro Hamanod.
Predictors of recurrent febrile seizures during the same febrile illness
in children with febrile seizures. Journal
of the Neurological Sciences. In press.
Highlights
•Incidence of recurrent febrile seizures during same febrile
illness (RFS) was 17.6%.
•Male sex and a body temperature ≤ 39.8 °C were independent
predictors of RFS.
•The two predictors combined had high sensitivity,
specificity, and negative predictive value.
Abstract
Febrile seizures (FS) are common in childhood. Of children
who experience an FS, 14–24% experience recurrence within 24 h, during the same
febrile illness (RFS). The aim of this pilot study was to identify the
predictors of RFS among children who experience FS. We conducted a
retrospective cohort study of children aged 6–60 months, who visited the
emergency department (ED) at Atsugi City Hospital in Japan for treatment of an
FS between December 1, 2018 and February 28, 2019. Exclusion criteria included
multiple seizures before visiting the ED, diazepam administration before
visiting the ED or on departure, seizures lasting >15 min, underlying
diseases such as epilepsy, and absence of laboratory test results. The primary
outcome was RFS. Fifty-one patients fulfilled the inclusion criteria, of whom
nine (17.6%) had RFS. The incidence of RFS was significantly higher in children
with a body temperature ≤ 39.8 °C during the ED visit (P = .01). The
combination of male sex and a body temperature ≤ 39.8 °C had a sensitivity,
specificity and negative predictive value of 88.9%, 76.2%, and 97.0%,
respectively. In conclusion, the incidence of RFS was 17.6%. The major
predictors of RFS were male sex and a body temperature ≤ 39.8 °C.
Courtesy of: https://www.mdlinx.com/journal-summaries/body-temperature-childhood-febrile-illnesses-febrile/2020/01/17/7600045?spec=neurology
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