Jun Kubota, Norimichi Higurashib, Daishi Hiranob, Hirotaka Isonoa, Haruka Numata, Takayuki Suzukia, Daisuke Kakegawaa, Akira Itoa, Manabu Yoshihashic, Takeru Itoa, Shin-ichiro Hamanod. Predictors of recurrent febrile seizures during the same febrile illness in children with febrile seizures. Journal of the Neurological Sciences. In press.
•Incidence of recurrent febrile seizures during same febrile illness (RFS) was 17.6%.
•Male sex and a body temperature ≤ 39.8 °C were independent predictors of RFS.
•The two predictors combined had high sensitivity, specificity, and negative predictive value.
Febrile seizures (FS) are common in childhood. Of children who experience an FS, 14–24% experience recurrence within 24 h, during the same febrile illness (RFS). The aim of this pilot study was to identify the predictors of RFS among children who experience FS. We conducted a retrospective cohort study of children aged 6–60 months, who visited the emergency department (ED) at Atsugi City Hospital in Japan for treatment of an FS between December 1, 2018 and February 28, 2019. Exclusion criteria included multiple seizures before visiting the ED, diazepam administration before visiting the ED or on departure, seizures lasting >15 min, underlying diseases such as epilepsy, and absence of laboratory test results. The primary outcome was RFS. Fifty-one patients fulfilled the inclusion criteria, of whom nine (17.6%) had RFS. The incidence of RFS was significantly higher in children with a body temperature ≤ 39.8 °C during the ED visit (P = .01). The combination of male sex and a body temperature ≤ 39.8 °C had a sensitivity, specificity and negative predictive value of 88.9%, 76.2%, and 97.0%, respectively. In conclusion, the incidence of RFS was 17.6%. The major predictors of RFS were male sex and a body temperature ≤ 39.8 °C.
Courtesy of: https://www.mdlinx.com/journal-summaries/body-temperature-childhood-febrile-illnesses-febrile/2020/01/17/7600045?spec=neurology