15 year old adolescent asymptomatic female with neurofibromatosis and Beckwith-Weidemann treated with trimetinib for a progressively enlarging right cerebellar peduncular lesion. Serial images postcontrast T1.
See https://childnervoussystem.blogspot.com/2019/05/trametinib-for-progressive-pediatric.html https://childnervoussystem.blogspot.com/2015/05/venriculomegaly-in-nf1.html
8/17/2020 Right brachium pontis lesion enhances over an area of 17 x 15 mmwith local mass effect without distortion of fourth ventricle.
12/4/19 Slight decrease in the size of the enhancing focus in the right cerebellar hemisphere.
8/15/19 Significant improvement in the size and enhancement of lesions in the right basal ganglia, left cerebral peduncle, and right cerebellar peduncle compared to 05/06/2019
5/06/19 In addition, overall enhancement within the right middle cerebellar peduncle lesion has also increased from the prior study, with increased adjacent T2/FLAIR hyperintense signal in the right middle cerebellar peduncle and the right cerebellum.
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