Tuesday, December 20, 2016

Arterial ischemic stroke and celiac disease

Balci O, Sezer T. The Prevalence of Celiac Disease in Children With Arterial
Ischemic Stroke. J Pediatr Hematol Oncol. 2017 Jan;39(1):46-49.

The association between arterial ischemic stroke (AIS) and celiac disease (CD) has been described in only a few cases in adults and children. We aim to determine the prevalence of CD in children and adolescents with AIS.
We investigated serum levels of tissue transglutaminase antibody immunoglobulin (Ig)A and total IgA from 76 children with AIS and in a healthy control group of 102 children. Study participants who were positive for tissue transglutaminase IgA antibodies underwent a duodenal biopsy.
A total of 2 patients in the AIS group (2.26%) and 2 in the control group (1.96%) had positive serum tissue transglutaminase antibody (P=0.89; 95% confidence interval, -5.05 to 6.89). Duodenal biopsy confirmed CD in only 1 patient who had AIS.
In the present study, children with acute arterial stroke did not exhibit a higher prevalence rate of CD compared with healthy controls. Therefore, the screening test for CD is not a necessary part of the management of AIS in children. However, cases of recurrent AIS could be examined for CD.

Courtesy of:  https://www.mdlinx.com/neurology/medical-news-article/2016/12/20/arterial-ischemic-stroke-celiac-disease-children/6983010/?category=latest&page_id=1

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